GD1-69
A human anti-spike protein (SARS-CoV-2) antibody.
General information
GD1-69 is a human antibody potently neutralizing the SARS-CoV-2 spike protein. It was originally identified in a single-cell analysis of B cells of COVID-19 patients (Li et al., 2020).
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
Single cell RNA and immune repertoire profiling of COVID-19 patients reveal novel neutralizing antibody
Spike protein In vitro Antibody |
in vitro binding assay; Vero E6 cells | 10.16 | The antibody bound RBD of the SARS-CoV-2 spike protein with high affinity (IC50 = 0.26 μg/mL). It also neutralized SARS-CoV-2 pseudovirus (IC50 = 1.77 μg/mL) and live virus (IC50 = 0.44 μg/mL) in vitro. |
Nov/25/2020 |
