Flupentixol
A thioxanthene dopamine D1 and D2 receptor antagonist.
General information
Flupentixol is an antipsychotic neuroleptic thioxanthene. It acts as a dopamine D1 and D2 receptor antagonist (DrugBank).
Flupentixol on PubChem
Flupentixol on Wikipedia
Marketed as
DEPIXOL; FLUANXOL; FLUPENTIXOL DECANOATE; JEXIT
![Structure image - Flupentixol](/data/images/941.png)
C1CN(CCN1CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO
Supporting references
Link | Tested on | Impact factor | Notes | Publication date |
---|---|---|---|---|
Identification of SARS-CoV-2 entry inhibitors among already approved drugs
Small molecule In vitro Screening |
Huh-7 cells (pseudovirus-based assay); Vero E6 cells (antiviral activity); SARS-CoV-2 (WIV04) | 5.06 | Inhibits SARS-CoV-2 spike protein pseudovirus cell entry and significally inhibits viral replication in vitro. |
Oct/28/2020 |