Other substances

Etravirine

A non-nucleoside reverse transcriptase inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Used to treat other disease

2
 Supporting references
0
 Contradictory references
2
 AI-suggested references
0
 Clinical trials

General information

Etravirine on PubChem

 

Structure image - Etravirine

CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N

Supporting references

Link Tested on Impact factor Notes Publication date
Predicting commercially available antiviral drugs that may act on the novel coronavirus (2019-nCoV), Wuhan, China through a drug-target interaction deep learning model
Preprint In silico 		in silico Feb/02/2020
Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach
3CLpro RdRpol Small molecule In silico 		in silico 2.45

Predicted to bind both SARS-CoV-2 3C-like protease and RNA-dependent RNA polymerase. It also possesses predicted good bioavailability.

 Oct/26/2020

AI-suggested references

Link Publication date
Identification of Entry Inhibitors against Delta and Omicron Variants of SARS-CoV-2.
Apr/06/2022
Tocilizumab in HIV patient with severe COVID-19: case report
Oct/16/2021
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