Other substances

Ethyl 3-hydroxy-6-methyl-4-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoate

A putative protease inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Ethyl 3-hydroxy-6-methyl-4-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoate is a theoretical SARS-CoV-2 3C-like protease inhibitor (Aghaee et al., 2021).

Ethyl 3-hydroxy-6-methyl-4-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoate on PubChem

Synonyms

Pubchem44326934; CHEMBL94638

 

Structure image - Ethyl 3-hydroxy-6-methyl-4-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoate

CCOC(=O)CC(C(CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C)O

Supporting references

Link Tested on Impact factor Notes Publication date
In silico exploration of novel protease inhibitors against coronavirus 2019 (COVID-19)
3CLpro Small molecule In silico 		in silico 1.28

Predicted to bind the SARS-CoV-2 3C-like protease.

 Jan/12/2021
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