Other substances

Erythrosine

A food dye.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
2
 AI-suggested references
0
 Clinical trials

General information

Erythrosine is a xanthene food dye. It manifests some (geno)toxicity (Chequer et al., 2012).

Erythrosine on PubChem
Erythrosine on Wikipedia

Synonyms

Food Red No. 3; Erythrosin B; Erythrosine B; E127; ErB

 

Structure image - Erythrosine

C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)[O-])I)I)[O-])I.[Na+].[Na+]

Supporting references

Link Tested on Impact factor Notes Publication date
Methylene Blue Inhibits the SARS-CoV-2 Spike–ACE2 Protein-Protein Interaction–a Mechanism that can Contribute to its Antiviral Activity Against COVID-19
Spike protein ACE2 Small molecule In vitro 		in vitro binding assay; hACE-expressing HEK293T cells; SARS-CoV-2 Spike pseudovirus 4.23

Inhibits the interaction between SARS-CoV-2 Spike and the host’s ACE2 receptor in vitro in a dose-dependent manner with IC50 of 0.4 μM.

 Jan/13/2021

AI-suggested references

Link Publication date
Methylene Blue Inhibits the SARS-CoV-2 Spike-ACE2 Protein-Protein Interaction-a Mechanism that can Contribute to its Antiviral Activity Against COVID-19.
Jan/13/2021
The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells
Jan/05/2022
Export (.csv)