Other substances

Ergosterol

A fungal sterol

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
3
 AI-suggested references
0
 Clinical trials

General information

Ergosterol on PubChem

Synonyms

Provitamin D2

 

Structure image - Ergosterol

C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC=C4[C@@]3(CC[C@@H](C4)O)C)C

Supporting references

Link Tested on Impact factor Notes Publication date
Mushroom-derived bioactive compounds potentially serve as the inhibitors of SARS-CoV-2 main protease: An in silico approach
3CLpro Small molecule In silico 		in silico 3.08

Predicted to inhibit the SARS-CoV-2 3C-like protease.

 Jan/04/2021

AI-suggested references

Link Publication date
Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-kappaB and p38/MAPK signaling pathways in vitro.
Jan/22/2021
Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis
Apr/04/2022
Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine
Oct/01/2021
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