Other substances

Enoximone

A phosphodiesterase inhibitor.

Phase of research

Potential treatment - clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Enoximone is a selective phosphodiesterase 3 inhibitor used for the treatment of congestive heart failure (DrugBank).

Enoximone on PubChem
Enoximone on Wikipedia

Synonyms

Fenoximone

Marketed as

PERFAN

 

Structure image - Enoximone

CC1=C(NC(=O)N1)C(=O)C2=CC=C(C=C2)SC

Supporting references

Link Tested on Impact factor Notes Publication date
PDE3-inhibitor enoximone prevented mechanical ventilation in patients with SARS-CoV-2 pneumonia
Small molecule Case report 		Emergent respiratory failure COVID-19 patients 1.70

Rapid recovery from emerging respiratory failure was observed. Sample size: 4. Dosage: IV 20 mg bolus; 10 mg/h perfusion for ca. 24-48 hours.

 Feb/05/2021

AI-suggested references

Link Publication date
The Potential Role of Aerosolized Phosphodiesterase 3 Inhibitor Enoximone in the Management of Coronavirus Disease 2019 Hypoxemia: A Case Report.
Jun/21/2021
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