Other substances

Ellagic acid

A bioactive tannin (polyphenol) compound.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Ellagic acid on PubChem

C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
An in-silico evaluation of dietary components for structural inhibition of SARS-Cov-2 main protease 3CLpro Small molecule In silico	in silico	3.31	Predicted to inhibit SARS-CoV-2 3C-like protease.	Aug/18/2020
In silico investigation of saponins and tannins as potential inhibitors of SARS-CoV-2 main protease (Mpro) 3CLpro Small molecule In silico	in silico		Predicted to inhibit the SARS-CoV-2 3C-like protease and have good pharmacokinetic properties and bioavailability.	Jan/06/2021

AI-suggested references

Link	Publication date
Nanoformulation Composed of Ellagic Acid and Functionalized Zinc Oxide Nanoparticles Inactivates DNA and RNA Viruses.	Dec/23/2021
Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants.	Jul/20/2020
A prospective observational study on oral administration of Ellagic Acid and Annona Muricata in patients affected by non-muscle invasive bladder cancer not undergoing maintenance after 6-week intravesical prophylaxis.	Jun/02/2021
Study on the mechanism of active components of Liupao tea on 3CLpro based on HPLC-DAD fingerprint and molecular docking technique.	Jul/05/2021
Identification of SARS-CoV-2 Receptor Binding Inhibitors by In Vitro Screening of Drug Libraries	Dec/03/2021
Promising phytochemicals of traditional Indian herbal steam inhalation therapy to combat COVID-19 - An in silico study.	Jan/04/2021
Antiviral phytocompounds "ellagic acid" and "(+)-sesamin" of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular docking, molecular dynamics simulation studies, binding free energy calculations, and bioactivi	May/10/2022
Dietary polyphenols mitigate SARS-CoV-2 main protease (Mpro) - Molecular Dynamics, Molecular Mechanics, and Density Functional Theory Investigations.	Jul/26/2021
Exploring the new potential antiviral constituents of Moringa oliefera for SARS-COV-2 pathogenesis: An in silico molecular docking and dynamic studies.	Jan/26/2021
Inhibitory Effects and Surface Plasmon Resonance-Based Binding Affinities of Dietary Hydrolyzable Tannins and Their Gut Microbial Metabolites on SARS-CoV-2 Main Protease	Mar/30/2022
Molecular Docking and ADMET Prediction of Natural Compounds towards SARS Spike Glycoprotein-Human Angiotensin-Converting Enzyme 2 and SARS-CoV-2 Main Protease.	Sep/01/2021
Computational study of pomegranate peel extract polyphenols as potential inhibitors of SARS-CoV-2 virus internalization	Nov/16/2020
In silico screening of potent bioactive compounds from honeybee products against COVID-19 target enzymes	May/02/2021

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