Dp44mT
An iron chelator.
General information
Dp44mT is an iron chelator (Dittmar et al., 2021).
Dp44mT on PubChem
Synonyms
3-(Dipyridin-2-ylmethylideneamino)-1,1-dimethylthiourea
CN(C)C(=S)NN=C(C1=CC=CC=N1)C2=CC=CC=N2
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
Small molecule In vitro Screening |
Huh7.5 cells; Calu-3 cells; primary normal human bronchial epithelial cells; iPSC-derived AT2 cells; SARS-CoV-2 strain USA WA1/2020 | 8.11 | Inhibited SARS-CoV-2 replication in Huh7.5 cells and also in Calu-3 cells with an SI of >3. |
Mar/23/2021 |
