Other substances

Diadenosine hexaphosphate

A (5'->5')-dinucleotide.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Diadenosine hexaphosphate on PubChem

Synonyms

P(1),P(6)-bis(5'-adenosyl)hexaphosphate

 

Structure image - Diadenosine hexaphosphate

C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N

Supporting references

Link Tested on Impact factor Notes Publication date
Drug similarity and structure-based screening of medicinal compounds to target macrodomain-I from SARS-CoV-2 to rescue the host immune system: a molecular dynamics study
nsp3 Small molecule In silico 		in silico 3.22

Predicted to bind the SARS-CoV-2 nsp3 macrodomain-I (Mac1/X-domain).

 Sep/08/2020
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