Other substances

Desethylamodiaquine

An amodiaquine metabolite.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Desethylamodiaquine is an amodiaquine primary metabolite.

Desethylamodiaquine on PubChem

 

Structure image - Desethylamodiaquine

CCNCC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O

Supporting references

Link Tested on Impact factor Notes Publication date
Antimalarial drugs inhibit the replication of SARS-CoV-2: An in vitro evaluation
Small molecule In vitro 		Vero E6 cells; SARS-CoV-2 IHUMI-3 strain 4.59

The antimalarial drug inhibited SARS-CoV-2 in vitro at IC50 and IC90 similar to the concentrations reached during oral antimalarial treatment.

 Sep/08/2020

AI-suggested references

Link Publication date
In Vitro Evaluation of the Antiviral Activity of Methylene Blue Alone or in Combination against SARS-CoV-2.
Jul/06/2021
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