Other substances

Demethoxycurcumin

A curcuminoid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Demethoxycurcumin on PubChem

 

Structure image - Demethoxycurcumin

COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O

Supporting references

Link Tested on Impact factor Notes Publication date
In-silico screening of plant-derived antivirals against main protease, 3CLpro and endoribonuclease, NSP15 proteins of SARS-CoV-2
3CLpro nsp15 Small molecule In silico 		in silico 3.22

Predicted to inhibit the SARS-CoV-2 3C-like protease and the nsp15 endoribonuclease.

 Sep/08/2020

AI-suggested references

Link Publication date
The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket: a molecular dynamics simulation study.
Jul/19/2021
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