dbq33b4p7
A heterocyclic alkaloid.
General information
dbq33b4p7 is a tylophorine derivative with in vitro anti-SARS-CoV-2 activity (Yang et al., 2020).
CCN1CC2=C(C(O)C1C)C1=CC=C(OC)C=C1C1=CC(OC)=C(OC)C=C21
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives
Small molecule In vitro |
Vero E6 cells | 4.23 | Manifested in vitro anti-SARS-CoV-2 activity in Vero E6 cells with EC50 of20 nM in a cytopathic effect assay and 31.9 nM in an immunofluorescence assay, with a selectivity index of 125 or 93. |
Dec/14/2020 |