Other substances

Cytochalasin D

An actin polymerization inhibitor and stabilizer.

Phase of research

Potential treatment - theoretical effect

How it helps

Other treatment

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Cytochalasin D is a fungal metabolite that inhibits microfilament dynamics, which leads to multiple phenotypes including impairment of DNA synthesis, glucose transport, sperm motility, growth hormone release and thyroid secretion (MeSH).


Cytochalasin D on PubChem
Cytochalasin D on Wikipedia

 

Structure image - Cytochalasin D

C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3CC4=CC=CC=C4)C)O

Supporting references

Link Tested on Impact factor Notes Publication date
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
in silico 4.86

In silico screening of potential ACE2 agonists. Theoretical amelioration of ACE2 depletion by virus attachment.

 Jun/27/2020

AI-suggested references

Link Publication date
A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals.
Apr/30/2021
Export (.csv)