Clemastine
A first generation antihistamine.
General information
Clemastine is a first generation antihistamine, which acts as a H1-receptor antagonist and a muscarinic antagonist (ChEBI).
Clemastine on DrugBank
Clemastine on PubChem
Clemastine on Wikipedia
Marketed as
AGASTEN; ALLERHIST-1; CLEMASTINE FUMARATE; TAVEGIL; TAVEGYL; TAVIST; TAVIST-1
![Structure image - Clemastine](/data/images/688.png)
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Supporting references
Link | Tested on | Impact factor | Notes | Publication date |
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Identification of SARS-CoV-2 entry inhibitors among already approved drugs
Small molecule In vitro Screening |
Huh-7 cells (pseudovirus-based assay); Vero E6 cells (antiviral activity); SARS-CoV-2 (WIV04) | 5.06 | Inhibits SARS-CoV-2 spike protein pseudovirus cell entry and significally inhibits viral replication in vitro. Has the lowest EC50 value of the drugs tested in this study. |
Oct/28/2020 |
AI-suggested references
Link | Publication date |
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On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2.
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Aug/19/2020 |