Other substances

Ciprofloxacin

A fluoroquinolone antibiotic.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Used to treat other disease

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Ciprofloxacin on PubChem

Marketed as

CIPRO; OTIPRIO; CIPROFLOXACIN HYDROCHLORIDE; CIPROFLOXACIN; CETRAXAL (CIPROFLOXACIN HYDROCHLORIDE); CILOXAN (CIPROFLOXACIN HYDROCHLORIDE)

C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19 Spike protein Small molecule In silico	in silico	2.64	Predicted to block SARS-CoV-2 spike protein interaction with the host cell.	Jul/01/2020

AI-suggested references

Link	Publication date
Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues.	Oct/04/2021
Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4.	Mar/04/2021
Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis.	Oct/15/2020
Could Respiratory Fluoroquinolones, Levofloxacin and Moxifloxacin, Prove to be Beneficial as an Adjunct Treatment in COVID-19?	Jun/06/2020
Ciprofloxacin-Resistant Pseudomonas aeruginosa Lung Abscess Complicating COVID-19 Treated with the Novel Oral Fluoroquinolone Delafloxacin.	Feb/16/2022
In vitro inhibition and molecular docking of a new ciprofloxacin-chalcone against SARS-CoV-2 main protease	Jul/30/2021
The application of in silico experimental model in the assessment of ciprofloxacin and levofloxacin interaction with main SARS-CoV-2 targets: S-, E- and TMPRSS2 proteins, RNA-dependent RNA polymerase and papain-like protease (PLpro):preliminary molecular	May/30/2021
Target-based drug discovery, ADMET profiling and bioactivity studies of antibiotics as potential inhibitors of SARS-CoV-2 main protease (Mpro).	Jul/01/2021
Antimicrobial properties of diethylamine NONOate, a nitric oxide donor, against Escherichia coli: a pilot study	Dec/28/2020
In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19.	Jul/01/2020
Fosfomycin Vs Ciprofloxacin as Oral Step-Down Treatment for Escherichia coli Febrile Urinary Tract Infections in Women: A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial	May/13/2020

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