Other substances

Cilomilast

A phosphodiesterase inhibitor.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Other treatment

Drug status

Experimental

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 Clinical trials

General information

Cilomilast is a drug developed for the treatment of respiratory disorders. It acts as a selective phosphodiesterase-4 inhibitor (DrugBank).

Cilomilast on PubChem
Cilomilast on Wikipedia

Synonyms

Ariflo, SB-207499

 

Structure image - Cilomilast

COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3

Supporting references

Link Tested on Impact factor Notes Publication date
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
GES1 cells; M0 and M1 macrophages 4.86

Decreases IL-6 secretion in M1 macrophages in vitro.

 Jun/27/2020
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