Calcitriol
The active form of vitamin D3.
General information
Calcitriol is a synthetic physiologically-active analog of vitamin D, specifically the vitamin D3 form. Calcitriol regulates calcium in vivo by promoting absorption in the intestine, reabsorption in the kidneys, and, along with parathyroid hormone, regulation of bone growth.
Calcitriol on DrugBank
Calcitriol on PubChem
Calcitriol on Wikipedia
Synonyms
1,25-Dihydroxyvitamin D, 1,25-Dihydroxycholecaliferol
Marketed as
ASENTAR; CALCITRIOL; DECOSTRIOL; ROCALTROL; SILKIS; VECTICAL
CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
Calcitriol, the active form of vitamin D, is a promising candidate for COVID-19 prophylaxis
Preprint |
VERO E6, HuH7 and human nasal epithelial cells | Jun/22/2020 | ||
|
Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction
Small molecule In vitro |
in vitro binding assay; HEK 293T cells; Vero E6 cells; Calu-3 cells | 10.16 | Disrupted (mildly) ACE2-RBD (of SARS-CoV-2 spike protein) interaction in vitro in a dose-dependent manner. |
Nov/18/2020 |
