Other substances

Caffeine

A xanthine alkaloid

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
7
 AI-suggested references
0
 Clinical trials

General information

Caffeine on PubChem

Marketed as

CAFCIT; CAFFEDRINE; CAFFEINE CITRATE; DEXITAC; DURVITAN; ENERJETS; NO-DOZ; PEYONA; PEP-BACK; QUICK PEP; WAKE-UP

 

Structure image - Caffeine

CN1C=NC2=C1C(=O)N(C(=O)N2C)C

Supporting references

Link Tested on Impact factor Notes Publication date
In silico Investigation on the Inhibiting Role of Nicotine/Caffeine by Blocking the S Protein of SARS-CoV-2 Versus ACE2 Receptor
Spike protein ACE2 Small molecule In silico 		in silico 4.17

Predicted to bind the host ACE2 receptor in the presence of the SARS-CoV-2 spike (S) protein, which could block ACE2-S interaction. In combination with <a href=

 Oct/17/2020

AI-suggested references

Link Publication date
Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants.
Jul/20/2020
Study on the mechanism of active components of Liupao tea on 3CLpro based on HPLC-DAD fingerprint and molecular docking technique.
Jul/05/2021
Methylxanthines as Potential Inhibitor of SARS-CoV-2: an In Silico Approach
Mar/08/2022
Possible Beneficial Actions of Caffeine in SARS-CoV-2
May/22/2021
Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2
Oct/23/2020
COVID-19 Associated Wake-Up Stroke Treated With DWI/FLAIR Mismatch Guided Intravenous Alteplase
Nov/04/2021
Potential prophylactic efficacy of mast cell stabilizers against COVID-19 vaccine-induced anaphylaxis
May/07/2020
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