Other substances

Brincidofovir

An ether lipid ester analogue of cidofovir.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Brincidofovir on DrugBank
Brincidofovir on PubChem

 

Structure image - Brincidofovir

CCCCCCCCCCCCCCCCOCCCOP(=O)(CO[C@@H](CN1C=CC(=NC1=O)N)CO)O

Supporting references

Link Tested on Impact factor Notes Publication date
Molecular docking suggests repurposing of brincidofovir as a potential drug targeting SARS-CoV-2 ACE2 receptor and main protease
3CLpro ACE2 Small molecule In silico 		in silico 1.06

Predicted to bind both the human ACE2 receptor and the SARS-CoV-2 3C-like protease.

 Aug/08/2020

AI-suggested references

Link Publication date
Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model
Feb/03/2021
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