Other substances

Bisdemethoxycurcumin

A curcuminoid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

2
 Supporting references
0
 Contradictory references
2
 AI-suggested references
0
 Clinical trials

General information

Bisdemethoxycurcumin on PubChem

Synonyms

Bis-demethoxy curcumin

 

Structure image - Bisdemethoxycurcumin

C1=CC(=CC=C1/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O

Supporting references

Link Tested on Impact factor Notes Publication date
In-silico screening of plant-derived antivirals against main protease, 3CLpro and endoribonuclease, NSP15 proteins of SARS-CoV-2
3CLpro nsp15 Small molecule In silico 		in silico 3.22

Predicted to inhibit the SARS-CoV-2 3C-like protease and the nsp15 endoribonuclease.

 Sep/08/2020
Virtual screening of curcumin and its analogs against the spike surface glycoprotein of SARS-CoV-2 and SARS-CoV
Spike protein Small molecule In silico 		in silico 3.22

Predicted to inhibit SARS-CoV-2 Spike protein.

 Jan/05/2021

AI-suggested references

Link Publication date
In silico study on spice-derived antiviral phytochemicals against SARS-CoV-2 TMPRSS2 target.
Aug/24/2021
The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket: a molecular dynamics simulation study.
Jul/19/2021
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