Birinapant

A peptidomimetic antagonist of Second Mitochondrial-derived Activator of Caspases and Inhibitor of Apoptosis Protein.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
Supporting references
0
Contradictory references
2
AI-suggested references
0
Clinical trials

General information

Birinapant on PubChem

 

Structure image - Birinapant

CC[C@@H](C(=O)N1C[C@H](C[C@H]1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)C[C@@H]6C[C@@H](CN6C(=O)[C@H](CC)NC(=O)[C@H](C)NC)O)O)NC(=O)[C@H](C)NC


Supporting references

Link Tested on Impact factor Notes Publication date
Molecular docking and simulation studies on SARS-CoV-2 Mpro reveals Mitoxantrone, Leucovorin, Birinapant, and Dynasore as potent drugs against COVID-19
3CLpro Small molecule In silico
in silico 3.31

Predicted to inhibit SARS-CoV-2 3C-like protease.

Aug/20/2020

AI-suggested references