Berbamine hydrochloride
General information
Berbamine hydrochloride on PubChem
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC.Cl
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
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Comparative analysis of antiviral efficacy of FDA-approved drugs against SARS-CoV-2 in human lung cells: Nafamostat is the most potent antiviral drug candidate
Preprint |
Calu-3 human airway epithelial cells | higher IC50 value in Calu-3 cells than VERO E6 cells |
May/12/2020 | |
|
Predicted therapeutic targets for COVID-19 disease by inhibiting SARS-CoV-2 and its related receptors
ACE2 RNA TMPRSS2 Small molecule In silico |
in silico | 2.11 | Predicted to bind human ACE2, GRP78, AT1R, and TMPRSS2 receptors. |
Aug/07/2020 |
AI-suggested references
| Link | Publication date |
|---|---|
|
Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion
|
Apr/21/2021 |
