Basiliximab

An anti-IL-2R alpha chimeric antibody.

Phase of research

Potential treatment - theoretical effect

How it helps

Other treatment

Drug status

Used to treat other disease

1
Supporting references
0
Contradictory references
1
AI-suggested references
1
Clinical trials

General information

Basiliximab on DrugBank


Marketed as

SIMULECT

 

Structure image - Basiliximab

Supporting references

Link Tested on Impact factor Notes Publication date
Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection
Protein factor Small molecule Antibody In silico
in silico (machine learning) 13.49

Considered by the authors to be among the most relevant drugs identified in a machine-learning algorithm-based screening of compounds which considers causal protein-protein interactions, known drug targets, and specific signalling circuits in <a href=

Dec/11/2020

AI-suggested references

Clinical trials

ID Title Status Phase Start date Completion date
NCT05013034 Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients Not yet recruiting Phase 2 Oct/15/2021 Dec/01/2022
  • Alternative id - FWCSWG-COVID19-01
  • Interventions - Drug: Basiliximab Injection|Drug: Placebo
  • Study type - Interventional
  • Study results - No Results Available
  • Locations -
  • Study designs - Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|Primary Purpose: Treatment
  • Enrollment - 300
  • Age - 18 Years and older   (Adult, Older Adult)
  • Outcome measures - Primary Efficacy Endpoint|Avoidance of escalation of O2 therapy|Overall Survival|ICU Free Survival|ECMO Free Survival|Overall Survival at 90 days|Ventilator-free survival at 90 days