anti-spike-S1 IgYs

Chicken egg yolk antibodies.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

Supporting references

Contradictory references

AI-suggested references

Clinical trials

Anti-spike-S1 IgYs are egg yolk antibodies from hens that had been immunized with the SARS-CoV-2 spike protein S1 domain (Wei et al., 2020).

Link	Tested on	Impact factor	Notes	Publication date
Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2 Spike protein In vitro Antibody	hACE2 expressing HeLa cells	3.94	The polyclonal IgY antibodies bound to SARS-CoV-2 spike protein and neutralized the corresponding pseudotyped virus with IC50 of 270.5 μg/mL in vitro.	Nov/03/2020