Other substances

Anti-SARS-CoV-2 monobody clone 6b

An anti-SARS-CoV-2 monobody.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Anti-SARS-CoV-2 monobody clone 6b was identified using selection against the SARS-CoV-2 spike protein S1 subunit via a modified TRAP display method (Kondo et al., 2020).

 

Supporting references

Link Tested on Impact factor Notes Publication date
Antibody-like proteins that capture and neutralize SARS-CoV-2
Spike protein ACE2 In vitro Antibody 		in vitro binding assay; Vero E6 TMPRSS2 expressing cells 13.12

Inhibits the interaction between the SARS-CoV-2 spike protein S1 subunit and the host's ACE2 receptor and displays stong virus-neutralizing activity in vitro.

 Sep/18/2020
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