Other substances

Ad5-S-nb2

An adenovirus-vectored COVID-19 vaccine.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Vaccine

Drug status

Experimental

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Ad5-S-nb2 is an experimental replication-incompetent recombinant adenovirus serotype 5 vaccine. It carries a codon optimized SARS-CoV-2 S protein gene (Feng et al., 2020).

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques Spike protein Viral vector Animal model	BALB/c mice; Chinese rhesus macaques	12.12	Intramuscular injection of the vaccine elicited systemic antibody response against the SARS-CoV-2 spike protein and cell-mediated immune response, which was weaker after intranasal administration. The vaccine protected macaques from infection.	Aug/21/2020

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