Other substances

Acarbose

A pseudotetrasaccharide alpha-glucosidase and pancreatic alpha-amylase inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Used to treat other disease

3
 Supporting references
0
 Contradictory references
2
 AI-suggested references
0
 Clinical trials

General information

Acarbose on PubChem

Synonyms

Acarbosa

Marketed as

ACARBOSE; GLUCOBAY; PRANDASE; PRECOSE

 

Structure image - Acarbose

C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO

Supporting references

Link Tested on Impact factor Notes Publication date
In silico identification of drug candidates against COVID-19
3CLpro RdRpol 		in silico 2.11

Predicted to inhibit the SARS-CoV-2 3C-like protease.

 Oct/20/2020
MCCS: a novel recognition pattern-based method for fast track discovery of anti-SARS-CoV-2 drugs
3CLpro Small molecule In silico 		in silico 8.99

Predicted to inhibit the SARS-CoV-2 3C-like protease.

 Oct/20/2020
Reprofiling of approved drugs against SARS-CoV-2 main protease: an in-silico study
3CLpro Polysaccharide Small molecule In silico 		in silico 3.22

Predicted to inhibit the SARS-CoV-2 3C-like protease.

 Nov/12/2020

AI-suggested references

Link Publication date
Quantitative structure-activity relationships, molecular docking and molecular dynamics simulations reveal drug repurposing candidates as potent SARS-CoV-2 main protease inhibitors.
Jan/19/2022
Inpatient use of metformin and acarbose is associated with reduced mortality of COVID-19 patients with type 2 diabetes mellitus
Oct/09/2021
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