Ac-QS5-VS

A synthetic modified peptide.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

1
Supporting references
0
Contradictory references
0
AI-suggested references
0
Clinical trials

General information

Ac-QS5-VS is a synthetic modified peptide with inhibitory activity on the SARS-CoV-2 3C-like protease in vitro (Rut et al., 2020).


Synonyms

Ac-Abu-DTyr-Leu-Gln-VS

 

Acetyl-Abu-DTyr-Leu-Gln-vinyl sulfone


Supporting references

Link Tested on Impact factor Notes Publication date
SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging
Small molecule Enzyme assay Peptide In vitro
in vitro enzyme assay; HeLa and HEK-293T cell lysates; Huh7 cells; SARS-CoV-2 strain BetaCov/Belgium/GHB-03021/2020 (EPI ISL 407976, 3 February 2020) 12.59

Inhibited the SARS-CoV-2 3C-like protease in vitro at non-cytotoxic levels.

Oct/22/2020