Other substances

7-Bromo-3-[(7-bromo-4-hydroxy-2-oxo-1H-quinolin-3-yl)methyl]-4-hydroxy-1H-quinolin-2-one

A 2-quinolone derivative.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

7-Bromo-3-[(7-bromo-4-hydroxy-2-oxo-1H-quinolin-3-yl)methyl]-4-hydroxy-1H-quinolin-2-one on PubChem

Synonyms

3,3′-Methylenebis(7-bromo-4-hydroxyquinolin-2(1H)-one); 3e 2-quinolone derivate

 

Structure image - 7-Bromo-3-[(7-bromo-4-hydroxy-2-oxo-1H-quinolin-3-yl)methyl]-4-hydroxy-1H-quinolin-2-one

C1=CC2=C(C=C1Br)NC(=O)C(=C2O)CC3=C(C4=C(C=C(C=C4)Br)NC3=O)O

Supporting references

Link Tested on Impact factor Notes Publication date
Synthesis of 3,3′-methylenebis(4-hydroxyquinolin-2(1H)-ones) of prospective anti-COVID-19 drugs
3CLpro Small molecule In silico 		adenocarcinomic human alveolar basal epithelial cells 2.01

Predicted to inhibit the SARS-CoV-2 3C-like protease.

 Sep/14/2020
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