Other substances

5-Imidazol-1-ylmethyl-quinolin-8-ol

An experimental bromodomain-containing protein 4 inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

5-Imidazol-1-ylmethyl-quinolin-8-ol on PubChem

Synonyms

5-((1H-imidazol-1-yl)methyl)quinolin-8-ol; DD1

 

Structure image - 5-Imidazol-1-ylmethyl-quinolin-8-ol

C1=CC2=C(C=CC(=C2N=C1)O)CN3C=CN=C3

Supporting references

Link Tested on Impact factor Notes Publication date
5-((1H-imidazol-1-yl)methyl)quinolin-8-ol as potential antiviral SARS-CoV-2 candidate: Synthesis, crystal structure, Hirshfeld surface analysis, DFT and molecular docking studies
3CLpro nsp3 Small molecule In silico 		in silico 2.46

Predicted to interact with the SARS-CoV-2 3C-like protease and ADP ribose phosphatase nsp3.

 Jan/27/2021
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