Other substances

4-{[5-(2-Nitrophenyl)-2-furyl] methylene}-3-phenyl-5(4H)-isoxazolone

An experimental anti HIV-1 drug.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

4-{[5-(2-Nitrophenyl)-2-furyl] methylene}-3-phenyl-5(4H)-isoxazolone on PubChem

 

Structure image - 4-{[5-(2-Nitrophenyl)-2-furyl] methylene}-3-phenyl-5(4H)-isoxazolone

C1=CC=C(C=C1)C\2=NOC(=O)/C2=C\C3=CC=C(O3)C4=CC=CC=C4[N+](=O)[O-]

Supporting references

Link Tested on Impact factor Notes Publication date
Virtual screening of anti-HIV1 compounds against SARS-CoV-2: machine learning modeling, chemoinformatics and molecular dynamics simulation based analysis
3CLpro Small molecule In silico 		in silico 4.00

Predicted to interact with amino acid residues of SARS-CoV-2 3C-like protease critical for the enzyme's catalitic activity.

 Nov/23/2020
Export (.csv)