Other substances

2-Bromo-3-fluoro-N-[(1-methyl-1H-indol-3-yl)sulfonyl]benzamide

A protease inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

2-Bromo-3-fluoro-N-[(1-methyl-1H-indol-3-yl)sulfonyl]benzamide on PubChem

Synonyms

121558793

 

Structure image - 2-Bromo-3-fluoro-N-[(1-methyl-1H-indol-3-yl)sulfonyl]benzamide

CN1C=C(C2=CC=CC=C21)S(=O)(=O)NC(=O)C3=C(C(=CC=C3)F)Br

Supporting references

Link Tested on Impact factor Notes Publication date
Establishing an Analogue Based In Silico Pipeline in the Pursuit of Novel Inhibitory Scaffolds against the SARS Coronavirus 2 Papain-Like Protease
PapainLpro Small molecule In silico 		in silico 3.27

The compound was predicted to bind SARS-CoV-2 Papain-like protease (with similar affinity as GRL0617), have moderate water solubility, and good lipophilicity. It does not contain toxic chemical groups and was predicted to have fewer off-target protein interactions compared to GRL0617.

 Feb/20/2021
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