Other substances

2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide

A novel putative SARS-CoV-2 3C-like protease inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide is a novel putative anti-SARS-CoV-2 drug targeting the 3C-like protease (Mary et al., 2020).

2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide on PubChem

 

Structure image - 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide

C1=CC(=CC=C1NC(=O)CSC2=NC(=CC(=N2)N)N)F

Supporting references

Link Tested on Impact factor Notes Publication date
Quantum chemical insight into molecular structure, NBO analysis of the hydrogen-bonded interactions, spectroscopic (FT–IR, FT–Raman), drug likeness and molecular docking of the novel anti COVID-19 molecule...
3CLpro Novel compound Small molecule In silico 		in silico 3.23

Predicted to irreversibly interact with the SARS-CoV-2 3C-like protease.

 Aug/12/2020

AI-suggested references

Link Publication date
Quantum chemical insight into molecular structure, NBO analysis of the hydrogen-bonded interactions, spectroscopic (FT-IR, FT-Raman), drug likeness and molecular docking of the novel anti COVID-19 molecule 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluo
Aug/12/2020
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