Other substances

2-(3-(3-Chloro-4-fluorobenzoyl)-7-fluoro-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl)-N-(4-(trifluoromethyl)phenyl)acetamide

A cyclic sulfonamide derivative.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

2-(3-(3-Chloro-4-fluorobenzoyl)-7-fluoro-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl)-N-(4-(trifluoromethyl)phenyl)acetamide is a cyclic sulfonamide derivative with anti-SARS-CoV-2 activity in vitro (Shin et al., 2020).

Synonyms

13c cyclic sulfonamide

 

C1=CC(=CC4=C1C(=C(C(C2=CC=C(C(=C2)C)F)=O)N(CC(=O)N(C3=CC=C(C=C3)C(F)(F)F)[H])[S]4(=O)=O)O[H])F

Supporting references

Link Tested on Impact factor Notes Publication date
Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2
Small molecule In vitro 		Vero cells; SARS-CoV-2 (βCoV/KOR/KCDC03/2020) 2.64

Inhibited SARS-CoV-2 in vitro, whithout significant cytotoxicity.

 Nov/04/2020
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