Other substances

1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide

An N-substituted isatin compound.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide on PubChem

Synonyms

N-substituted isatin compound 26

 

Structure image - 1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide

C1=C(C=CC2=C1C(C(N2CC3=CC=C4C(=C3)C=CC=C4)=O)=O)C(=O)N([H])[H]

Supporting references

Link Tested on Impact factor Notes Publication date
Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds
3CLpro Small molecule Enzyme assay In vitro 		in vitro enzyme assay 5.57

The newly synthetized compound exhibited inhibitory activity on the SARS-CoV-2 3C-like protease in the in vitro enzyme assay.

 Aug/01/2020
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